Patient Resources for Living With Hereditary Angioedema(HAE)

Educational information about HAE, CINRYZE® (C1 esterase inhibitor [human]), and patient support services is available to download below.
For additional support and information, visit ryzeabove.com.

Hereditary Angioedema and You PDF

Hereditary Angioedema and You

This pamphlet created for you and your loved ones explains what HAE is, symptoms and common triggers, and the benefits of a preventive approach.

CINRYZE Patient Brochure PDF

CINRYZE Patient Brochure

This patient brochure gives an overview of CINRYZE and contains information on how it works to help prevent HAE attacks, how CINRYZE is made, and what to expect from therapy.

CINRYZE Solutions Brochure PDF

CINRYZESolutions Brochure

Learn how the CINRYZESolutions Support Program and its patient care coordinators can help your CINRYZE therapy go smoothly by finding information on working with your insurance company, locating financial assistance, coordinating delivery of CINRYZE, and more.

Path to Independence Brochure PDF

Path to Independence Brochure

This brochure explains the details available to you free of charge through this CINRYZESolutions Support
Program—infusion training for eligible patients who are starting self-administration with CINRYZE, and ongoing education and support for eligible patients who are receiving therapy with CINRYZE.

The following patient materials are available for download in English and Spanish:
CINRYZE Preparation and Self-Administration Instructions

Download the English Version ›

Download the Spanish Version ›

Do not attempt to self-administer unless you have been taught how by your healthcare provider.

Useful Links

The US Hereditary Angioedema Association

A non-profit patient advocacy organization dedicated to providing wide-ranging services to HAE patients and pioneering new HAE research. Our services include clinical trial placement, physician referrals, education, and individualized patient case management.

National Organization for Rare Disorders

NORD is a unique federation of individuals and organizations working together to build a better world for people affected by rare diseases.

American Academy of Allergy, Asthma, and Immunology

AAAAI works to support its 6,500 members worldwide in providing high-quality, compassionate healthcare for those with allergy, asthma, and immunologic disorders.

American College of Asthma, Allergy, and Immunology

The ACAAI is dedicated to improving the quality of patient care in allergy and immunology through research, advocacy, and professional public education.

World Allergy Organization

The WAO is an international umbrella organization that provides direct educational outreach programs, symposia, and lectureships to members in 92 countries.

Looking for Support?

Join the CINRYZEConnect™ Program to connect with a mentor who's also living with HAE and receiving therapy with CINRYZE.

Find out more ›

Help Prevent HAE Attacks

Frequency and severity of HAE attacks are unpredictable. Get more information on preventing your attacks.

Learn more ›

Indication
CINRYZE® (C1 esterase inhibitor [human]) is an injectable medicine that is used to help prevent swelling and/or painful attacks in teenagers and adults with Hereditary Angioedema (HAE).

Important Risk Information
You should not use CINRYZE if you have had life-threatening immediate hypersensitivity reactions, including anaphylaxis to the product.

Tell your healthcare provider about all of your medical conditions, including if you:

  • Are pregnant or planning to become pregnant. It is not known if CINRYZE can harm your unborn baby.
  • Are breastfeeding or plan to breastfeed. It is not known if CINRYZE passes into your milk and if it can harm your baby.
  • Have a history of blood clotting problems. Very high doses of C1 esterase inhibitor could increase the risk of blood clots.

Tell your healthcare provider and pharmacist about all of the medicines you take, including all prescription and non-prescription medicines such as over-the-counter medicines, supplements, or herbal remedies.

Allergic reactions may occur with CINRYZE. Call your healthcare provider or get emergency support services right away if you have any of the following symptoms:

  • wheezing
  • difficulty breathing
  • chest tightness
  • turning blue (look at lips and gums)
  • fast heartbeat
  • swelling of the face
  • faintness
  • rash
  • hives

Because CINRYZE is made from human blood, it may carry a risk of transmitting infectious agents, e.g., viruses and, theoretically, the Creutzfeldt-Jakob (CJD) agent.

The most common side effects seen with CINRYZE were headache, nausea, rash and vomiting. These are not all the possible side effects of CINRYZE. Tell your healthcare provider about any side effect that bothers you or that does not go away. You can also report side effects to the FDA at 1-800-FDA-1088.

Medicines are sometimes prescribed for purposes other than those listed here. Do not use CINRYZE for a condition for which it is not prescribed. Do not share CINRYZE with other people, even if they have the same symptoms that you have.

Before starting CINRYZE, please read the patient information and each time you get a refill. This information does not take the place of talking with your healthcare provider, and it does not include all of the important information about CINRYZE. If you have questions after reading this, ask your healthcare provider.

Please read the Full Prescribing Information.

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